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  3. It's kind of bonkers that estrogen HRT for transfems is still basically an "off-label" use for the medication.

It's kind of bonkers that estrogen HRT for transfems is still basically an "off-label" use for the medication.

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  • joscelyntransient@chaosfem.twJ joscelyntransient@chaosfem.tw

    It's kind of bonkers that estrogen HRT for transfems is still basically an "off-label" use for the medication.

    I was given an assignment to write a poem based upon a common documentation format, so chose to go with medication instructions and warnings paperwork. Reading the documentation for my estradiol, it's kind of hilarious to see that the uses are still just: menopause and ovarian failure for cis women or to treat prostate cancer in cis men. Trans women and transfeminine people are still not being considered one of the primary patient groups being treated by the medication in 2026.

    bel_tamtu@meemu.orgB This user is from outside of this forum
    bel_tamtu@meemu.orgB This user is from outside of this forum
    bel_tamtu@meemu.org
    wrote last edited by
    #15

    @JoscelynTransient I've noticed the same thing in the common documentation for my testosterone and transmascs. πŸ™ƒ It's all "not for use in females" blah blah blah. No mention of trans HRT.

    Which is wild because IIRC some very low dose T is sometimes given to post-menopausal women? Although in that case I suppose it's probably not the injection kind. I haven't seen documentation for gel yet.

    forestine@sunny.gardenF bright_helpings@mspsocial.netB 2 Replies Last reply
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    • joscelyntransient@chaosfem.twJ joscelyntransient@chaosfem.tw

      It's kind of bonkers that estrogen HRT for transfems is still basically an "off-label" use for the medication.

      I was given an assignment to write a poem based upon a common documentation format, so chose to go with medication instructions and warnings paperwork. Reading the documentation for my estradiol, it's kind of hilarious to see that the uses are still just: menopause and ovarian failure for cis women or to treat prostate cancer in cis men. Trans women and transfeminine people are still not being considered one of the primary patient groups being treated by the medication in 2026.

      0x4d6165@transfem.social0 This user is from outside of this forum
      0x4d6165@transfem.social0 This user is from outside of this forum
      0x4d6165@transfem.social
      wrote last edited by
      #16

      @JoscelynTransient@chaosfem.tw it's wild how many medications are like this, not just HRT (though of course there's a huge political factor here). I take a psych med as an adjunct to my antidepressant and it's off-label despite being well understood and multiple doctors have prescribed it to me so it seems "accepted" treatment

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      • bel_tamtu@meemu.orgB bel_tamtu@meemu.org

        @JoscelynTransient I've noticed the same thing in the common documentation for my testosterone and transmascs. πŸ™ƒ It's all "not for use in females" blah blah blah. No mention of trans HRT.

        Which is wild because IIRC some very low dose T is sometimes given to post-menopausal women? Although in that case I suppose it's probably not the injection kind. I haven't seen documentation for gel yet.

        forestine@sunny.gardenF This user is from outside of this forum
        forestine@sunny.gardenF This user is from outside of this forum
        forestine@sunny.garden
        wrote last edited by
        #17

        @Bel_tamtu @JoscelynTransient the gel documentation is the same. line drawing of cis guy with application areas shown, 'not for females' etc

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        • joscelyntransient@chaosfem.twJ joscelyntransient@chaosfem.tw

          It's kind of bonkers that estrogen HRT for transfems is still basically an "off-label" use for the medication.

          I was given an assignment to write a poem based upon a common documentation format, so chose to go with medication instructions and warnings paperwork. Reading the documentation for my estradiol, it's kind of hilarious to see that the uses are still just: menopause and ovarian failure for cis women or to treat prostate cancer in cis men. Trans women and transfeminine people are still not being considered one of the primary patient groups being treated by the medication in 2026.

          bright_helpings@mspsocial.netB This user is from outside of this forum
          bright_helpings@mspsocial.netB This user is from outside of this forum
          bright_helpings@mspsocial.net
          wrote last edited by
          #18

          @JoscelynTransient I had to sign a waiver saying I knew I am taking my testosterone for off-label reasons. Lots of warnings about not letting it touch a woman. It's just for men whose dick don't work good.

          sinvega@mas.toS 1 Reply Last reply
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          • bel_tamtu@meemu.orgB bel_tamtu@meemu.org

            @JoscelynTransient I've noticed the same thing in the common documentation for my testosterone and transmascs. πŸ™ƒ It's all "not for use in females" blah blah blah. No mention of trans HRT.

            Which is wild because IIRC some very low dose T is sometimes given to post-menopausal women? Although in that case I suppose it's probably not the injection kind. I haven't seen documentation for gel yet.

            bright_helpings@mspsocial.netB This user is from outside of this forum
            bright_helpings@mspsocial.netB This user is from outside of this forum
            bright_helpings@mspsocial.net
            wrote last edited by
            #19

            @Bel_tamtu @JoscelynTransient I found it very affirming that the leaflet with mine (gel, fwiw) is like "not for women! You must not let it touch a woman!" and I'm like "you're damn right!" as I slather it on. πŸ™‚

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            • joscelyntransient@chaosfem.twJ joscelyntransient@chaosfem.tw

              I'm also reminded of how absolutely pathetic it is that all these insecure manchildren want to pretend to be hardcore, edge-y, and cyberpunk....my guys, I'm out here hacking my biology with unapproved or even illegal application of pharmaceuticals as I take on the most wealthy and powerful individuals on the planet by living a life that they have declared both impossible and a crime. Oh, and I also smooch other gender criminals while looking badass with an undercut while people say that children merely seeing me will shake the foundations of the current world order.

              Just saying...being trans is pretty fucking badass.

              hal_pomeranz@infosec.exchangeH This user is from outside of this forum
              hal_pomeranz@infosec.exchangeH This user is from outside of this forum
              hal_pomeranz@infosec.exchange
              wrote last edited by
              #20

              @JoscelynTransient Meanwhile aging cishet guys like me with declining testosterone levels are basically getting high fives from the medical establishment as we show up for our regular testosterone boosts. The obvious double standard makes me crazy.

              You all truly are beautiful and badass. Respect.

              1 Reply Last reply
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              • joscelyntransient@chaosfem.twJ joscelyntransient@chaosfem.tw

                It's kind of bonkers that estrogen HRT for transfems is still basically an "off-label" use for the medication.

                I was given an assignment to write a poem based upon a common documentation format, so chose to go with medication instructions and warnings paperwork. Reading the documentation for my estradiol, it's kind of hilarious to see that the uses are still just: menopause and ovarian failure for cis women or to treat prostate cancer in cis men. Trans women and transfeminine people are still not being considered one of the primary patient groups being treated by the medication in 2026.

                floppyplopper@todon.nlF This user is from outside of this forum
                floppyplopper@todon.nlF This user is from outside of this forum
                floppyplopper@todon.nl
                wrote last edited by
                #21

                @JoscelynTransient
                listing transition as one of the uses of estradiol, might encourage more cis men to scott adams themselves. which is to say, do it πŸ‘

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                • bright_helpings@mspsocial.netB bright_helpings@mspsocial.net

                  @JoscelynTransient I had to sign a waiver saying I knew I am taking my testosterone for off-label reasons. Lots of warnings about not letting it touch a woman. It's just for men whose dick don't work good.

                  sinvega@mas.toS This user is from outside of this forum
                  sinvega@mas.toS This user is from outside of this forum
                  sinvega@mas.to
                  wrote last edited by
                  #22

                  @bright_helpings @JoscelynTransient expelling the air from a syringe of t and accidentally getting a drop on a woman, immediately causing her to writhe on the floor and spore off several angry little guys like a mogwai

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                  • purplestephyr@thetransagenda.gayP purplestephyr@thetransagenda.gay

                    @JoscelynTransient@chaosfem.tw I find T-blockers even funnier for this. Like side-effects of cyproterone are erectile dysfunction. Side-effect? No, that's a main-effect for a lot of transfems

                    jrdepriest@infosec.exchangeJ This user is from outside of this forum
                    jrdepriest@infosec.exchangeJ This user is from outside of this forum
                    jrdepriest@infosec.exchange
                    wrote last edited by
                    #23

                    @PurpleStephyr @JoscelynTransient

                    Erectile dysfunction is a permanent part of my medical record for some reason even though it's on purpose.

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                    • joscelyntransient@chaosfem.twJ joscelyntransient@chaosfem.tw

                      It's kind of bonkers that estrogen HRT for transfems is still basically an "off-label" use for the medication.

                      I was given an assignment to write a poem based upon a common documentation format, so chose to go with medication instructions and warnings paperwork. Reading the documentation for my estradiol, it's kind of hilarious to see that the uses are still just: menopause and ovarian failure for cis women or to treat prostate cancer in cis men. Trans women and transfeminine people are still not being considered one of the primary patient groups being treated by the medication in 2026.

                      guyjantic@infosec.exchangeG This user is from outside of this forum
                      guyjantic@infosec.exchangeG This user is from outside of this forum
                      guyjantic@infosec.exchange
                      wrote last edited by
                      #24

                      @JoscelynTransient this is weird but maybe understandable: labeled use usually (in the US) requires an FDA approval process, which requires a certain level of scientific evidence, which requires at least somewhat representative samples in treatment trials. This kind of research for HRT seems like it might be lacking, at least partly because of political shenanigans to restrict it, bit also probably because trans people willing to participate in drug trials might be a really small number... Which is almost certainly influenced by general and medical prejudice.

                      Not saying the pharmaceutical industry couldn't also be playing "appease the status quo sensibilities" for a few decades.

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