Skip to content
  • Categories
  • Recent
  • Tags
  • Popular
  • World
  • Users
  • Groups
Skins
  • Light
  • Brite
  • Cerulean
  • Cosmo
  • Flatly
  • Journal
  • Litera
  • Lumen
  • Lux
  • Materia
  • Minty
  • Morph
  • Pulse
  • Sandstone
  • Simplex
  • Sketchy
  • Spacelab
  • United
  • Yeti
  • Zephyr
  • Dark
  • Cyborg
  • Darkly
  • Quartz
  • Slate
  • Solar
  • Superhero
  • Vapor

  • Default (Cyborg)
  • No Skin
Collapse
Brand Logo

CIRCLE WITH A DOT

  1. Home
  2. Uncategorized
  3. Sigh.

Sigh.

Scheduled Pinned Locked Moved Uncategorized
87 Posts 54 Posters 16 Views
  • Oldest to Newest
  • Newest to Oldest
  • Most Votes
Reply
  • Reply as topic
Log in to reply
This topic has been deleted. Only users with topic management privileges can see it.
  • cstross@wandering.shopC cstross@wandering.shop

    Sigh.

    So it turns out we've mapped the neural connectome of Drosophila *and simulated it in silico*.

    Link Preview Image
    FlyWire

    favicon

    (flywire.ai)

    Pop-sci explainer here:

    Link Preview Image
    Whole Brain Emulation Achieved: Scientists Run a Fruit Fly Brain in Simulation | RathBiotaClan

    Scientists ran a real fruit fly brain in simulation using the FlyWire connectome, achieving the first working whole brain emulation.

    favicon

    RathBiotaClan (www.rathbiotaclan.com)

    Key quote: "The step from a complete connectome to a working computational brain model is not trivial." And there's an even more important finding in this screenshot (alt text via OCR):

    "The wiring is the computation".

    /1

    cstross@wandering.shopC This user is from outside of this forum
    cstross@wandering.shopC This user is from outside of this forum
    cstross@wandering.shop
    wrote last edited by
    #4

    The experimenters then went on to hook up their Drosophila connectome to an anatomically detailed Drosophila body model within an open-source physics engine that "uses generalized coordinates and constraint-based contact dynamics to simulate rigid-body systems with high fidelity" including joint and antennae modeling and accurate modeling of surface adhesion—and compound eye simulation.

    Lots of *really* interesting insights here.

    /2

    cstross@wandering.shopC robcornelius@climatejustice.socialR 2 Replies Last reply
    0
    • R relay@relay.infosec.exchange shared this topic
    • cstross@wandering.shopC cstross@wandering.shop

      The experimenters then went on to hook up their Drosophila connectome to an anatomically detailed Drosophila body model within an open-source physics engine that "uses generalized coordinates and constraint-based contact dynamics to simulate rigid-body systems with high fidelity" including joint and antennae modeling and accurate modeling of surface adhesion—and compound eye simulation.

      Lots of *really* interesting insights here.

      /2

      cstross@wandering.shopC This user is from outside of this forum
      cstross@wandering.shopC This user is from outside of this forum
      cstross@wandering.shop
      wrote last edited by
      #5

      They managed to run a feedback loop between the full 127,400 neuron network in the biological connectome to the physical simulation, with feedback from proprioceptive signals received by the model "fly" in the simulation producing feedback spile trains in the simulation, and THEY GOT RESULTS (again, see alt text of screencap: it's too verbose for a toot):

      /3

      cstross@wandering.shopC 1 Reply Last reply
      0
      • cstross@wandering.shopC cstross@wandering.shop

        Sigh.

        So it turns out we've mapped the neural connectome of Drosophila *and simulated it in silico*.

        Link Preview Image
        FlyWire

        favicon

        (flywire.ai)

        Pop-sci explainer here:

        Link Preview Image
        Whole Brain Emulation Achieved: Scientists Run a Fruit Fly Brain in Simulation | RathBiotaClan

        Scientists ran a real fruit fly brain in simulation using the FlyWire connectome, achieving the first working whole brain emulation.

        favicon

        RathBiotaClan (www.rathbiotaclan.com)

        Key quote: "The step from a complete connectome to a working computational brain model is not trivial." And there's an even more important finding in this screenshot (alt text via OCR):

        "The wiring is the computation".

        /1

        ehproque@neopaquita.esE This user is from outside of this forum
        ehproque@neopaquita.esE This user is from outside of this forum
        ehproque@neopaquita.es
        wrote last edited by
        #6

        @cstross I think I'm going to have to read that a few times to understand if

        1 Reply Last reply
        0
        • cstross@wandering.shopC cstross@wandering.shop

          The experimenters then went on to hook up their Drosophila connectome to an anatomically detailed Drosophila body model within an open-source physics engine that "uses generalized coordinates and constraint-based contact dynamics to simulate rigid-body systems with high fidelity" including joint and antennae modeling and accurate modeling of surface adhesion—and compound eye simulation.

          Lots of *really* interesting insights here.

          /2

          robcornelius@climatejustice.socialR This user is from outside of this forum
          robcornelius@climatejustice.socialR This user is from outside of this forum
          robcornelius@climatejustice.social
          wrote last edited by
          #7

          @cstross not lobsters then....

          cstross@wandering.shopC 1 Reply Last reply
          0
          • cstross@wandering.shopC cstross@wandering.shop

            Sigh.

            So it turns out we've mapped the neural connectome of Drosophila *and simulated it in silico*.

            Link Preview Image
            FlyWire

            favicon

            (flywire.ai)

            Pop-sci explainer here:

            Link Preview Image
            Whole Brain Emulation Achieved: Scientists Run a Fruit Fly Brain in Simulation | RathBiotaClan

            Scientists ran a real fruit fly brain in simulation using the FlyWire connectome, achieving the first working whole brain emulation.

            favicon

            RathBiotaClan (www.rathbiotaclan.com)

            Key quote: "The step from a complete connectome to a working computational brain model is not trivial." And there's an even more important finding in this screenshot (alt text via OCR):

            "The wiring is the computation".

            /1

            meyerweb@mastodon.socialM This user is from outside of this forum
            meyerweb@mastodon.socialM This user is from outside of this forum
            meyerweb@mastodon.social
            wrote last edited by
            #8

            @cstross Oh gods, Peter Watts was right.

            1 Reply Last reply
            0
            • cstross@wandering.shopC cstross@wandering.shop

              They managed to run a feedback loop between the full 127,400 neuron network in the biological connectome to the physical simulation, with feedback from proprioceptive signals received by the model "fly" in the simulation producing feedback spile trains in the simulation, and THEY GOT RESULTS (again, see alt text of screencap: it's too verbose for a toot):

              /3

              cstross@wandering.shopC This user is from outside of this forum
              cstross@wandering.shopC This user is from outside of this forum
              cstross@wandering.shop
              wrote last edited by
              #9

              There is stuff missing, of course (alt text for screencap contains about 3 toots' worth of text explaining this): information about how the motor neurons connect to physical features of the body like the muscles, information on morphologically divergent neurons and fine detail on dendritic branching and synaptic inputs across dendritic compartments:

              /4

              Link Preview Image
              cstross@wandering.shopC raymaccarthy@mastodon.ieR 2 Replies Last reply
              0
              • cstross@wandering.shopC cstross@wandering.shop

                There is stuff missing, of course (alt text for screencap contains about 3 toots' worth of text explaining this): information about how the motor neurons connect to physical features of the body like the muscles, information on morphologically divergent neurons and fine detail on dendritic branching and synaptic inputs across dendritic compartments:

                /4

                Link Preview Image
                cstross@wandering.shopC This user is from outside of this forum
                cstross@wandering.shopC This user is from outside of this forum
                cstross@wandering.shop
                wrote last edited by
                #10

                ... The next step on from Drosophila, the mouse brain, is 560 times larger—never mind a vastly more complex human brain. And to get the murine connectome we'll have to chop up *a lot* of brains: a human upload won't pass any kind of medical ethics review at this point!

                But near-term, it's expected to yield "fundamentally new architectural principles for AI systems that are more sample-efficient, more robust, and more capable of behavioral generalization than current approaches"

                /5

                cstross@wandering.shopC uilebheist@polyglot.cityU nilz@norden.socialN boydstephensmithjr@hachyderm.ioB mikestok@mstdn.caM 5 Replies Last reply
                0
                • cstross@wandering.shopC cstross@wandering.shop

                  ... The next step on from Drosophila, the mouse brain, is 560 times larger—never mind a vastly more complex human brain. And to get the murine connectome we'll have to chop up *a lot* of brains: a human upload won't pass any kind of medical ethics review at this point!

                  But near-term, it's expected to yield "fundamentally new architectural principles for AI systems that are more sample-efficient, more robust, and more capable of behavioral generalization than current approaches"

                  /5

                  cstross@wandering.shopC This user is from outside of this forum
                  cstross@wandering.shopC This user is from outside of this forum
                  cstross@wandering.shop
                  wrote last edited by
                  #11

                  But I'm REALLY HAPPY right now because this kinda-sorta validates the key premise of the SF novel I just handed in last month (which involves serial reincarnation via destructive brain-slicing-and-imaging then imprinting onto an immature cortex, and then explores its disastrous societal failure modes).

                  ... And it also hints that artificial consciousness might, eventually, be possible, if only via the hard path of doing it the same way we do it, only in simulation in silico.

                  /6 (ends)

                  mwl@io.mwl.ioM future_upbeat@mastodon.socialF jsl@hachyderm.ioJ raymaccarthy@mastodon.ieR antiqueight@mastodon.ieA 14 Replies Last reply
                  0
                  • cstross@wandering.shopC cstross@wandering.shop

                    But I'm REALLY HAPPY right now because this kinda-sorta validates the key premise of the SF novel I just handed in last month (which involves serial reincarnation via destructive brain-slicing-and-imaging then imprinting onto an immature cortex, and then explores its disastrous societal failure modes).

                    ... And it also hints that artificial consciousness might, eventually, be possible, if only via the hard path of doing it the same way we do it, only in simulation in silico.

                    /6 (ends)

                    mwl@io.mwl.ioM This user is from outside of this forum
                    mwl@io.mwl.ioM This user is from outside of this forum
                    mwl@io.mwl.io
                    wrote last edited by
                    #12

                    @cstross very cool, thanks for sharing!

                    cstross@wandering.shopC 1 Reply Last reply
                    0
                    • cstross@wandering.shopC cstross@wandering.shop

                      Sigh.

                      So it turns out we've mapped the neural connectome of Drosophila *and simulated it in silico*.

                      Link Preview Image
                      FlyWire

                      favicon

                      (flywire.ai)

                      Pop-sci explainer here:

                      Link Preview Image
                      Whole Brain Emulation Achieved: Scientists Run a Fruit Fly Brain in Simulation | RathBiotaClan

                      Scientists ran a real fruit fly brain in simulation using the FlyWire connectome, achieving the first working whole brain emulation.

                      favicon

                      RathBiotaClan (www.rathbiotaclan.com)

                      Key quote: "The step from a complete connectome to a working computational brain model is not trivial." And there's an even more important finding in this screenshot (alt text via OCR):

                      "The wiring is the computation".

                      /1

                      fromboliere@mastodon.unoF This user is from outside of this forum
                      fromboliere@mastodon.unoF This user is from outside of this forum
                      fromboliere@mastodon.uno
                      wrote last edited by
                      #13

                      @cstross apparently Aristotle was right about substance and essence

                      1 Reply Last reply
                      0
                      • cstross@wandering.shopC cstross@wandering.shop

                        But I'm REALLY HAPPY right now because this kinda-sorta validates the key premise of the SF novel I just handed in last month (which involves serial reincarnation via destructive brain-slicing-and-imaging then imprinting onto an immature cortex, and then explores its disastrous societal failure modes).

                        ... And it also hints that artificial consciousness might, eventually, be possible, if only via the hard path of doing it the same way we do it, only in simulation in silico.

                        /6 (ends)

                        future_upbeat@mastodon.socialF This user is from outside of this forum
                        future_upbeat@mastodon.socialF This user is from outside of this forum
                        future_upbeat@mastodon.social
                        wrote last edited by
                        #14

                        @cstross Agreed that artificial consciousness might be possible from the bottom up, starting with agency and a complete model.

                        I don't believe for a picosecond that current LLMs (or other AI) are conscious.

                        cstross@wandering.shopC 1 Reply Last reply
                        0
                        • robcornelius@climatejustice.socialR robcornelius@climatejustice.social

                          @cstross not lobsters then....

                          cstross@wandering.shopC This user is from outside of this forum
                          cstross@wandering.shopC This user is from outside of this forum
                          cstross@wandering.shop
                          wrote last edited by
                          #15

                          @robcornelius The Lobster stomatogastric ganglion sim happened in the 1990s. That's where I got the idea for "Lobsters" (written 1997/98) from.

                          1 Reply Last reply
                          0
                          • mwl@io.mwl.ioM mwl@io.mwl.io

                            @cstross very cool, thanks for sharing!

                            cstross@wandering.shopC This user is from outside of this forum
                            cstross@wandering.shopC This user is from outside of this forum
                            cstross@wandering.shop
                            wrote last edited by
                            #16

                            @mwl Also very cool, the Indian sci/tech news website that ran that feature! (From the writing style I initially thought it might be AI slop, but no: Indian English is just a bit different.)

                            pwassonchat@eldritch.cafeP solitha@mastodon.socialS 2 Replies Last reply
                            0
                            • cstross@wandering.shopC cstross@wandering.shop

                              There is stuff missing, of course (alt text for screencap contains about 3 toots' worth of text explaining this): information about how the motor neurons connect to physical features of the body like the muscles, information on morphologically divergent neurons and fine detail on dendritic branching and synaptic inputs across dendritic compartments:

                              /4

                              Link Preview Image
                              raymaccarthy@mastodon.ieR This user is from outside of this forum
                              raymaccarthy@mastodon.ieR This user is from outside of this forum
                              raymaccarthy@mastodon.ie
                              wrote last edited by
                              #17

                              @cstross
                              Also shows that much "AI" terminology is marketing, not science. Computer "AI" doesn't have Neural Networks (it's a distributed dataflow database) nor "learning".

                              I've suspected this result for decades.

                              "Uploading" human consciousness is still SF based on Transhumanism, which is a religion, not science.

                              I doubt it will yield anything for computer AI. Except current LLM based AI is a dead end.

                              1 Reply Last reply
                              0
                              • future_upbeat@mastodon.socialF future_upbeat@mastodon.social

                                @cstross Agreed that artificial consciousness might be possible from the bottom up, starting with agency and a complete model.

                                I don't believe for a picosecond that current LLMs (or other AI) are conscious.

                                cstross@wandering.shopC This user is from outside of this forum
                                cstross@wandering.shopC This user is from outside of this forum
                                cstross@wandering.shop
                                wrote last edited by
                                #18

                                @future_upbeat

                                I absolutely agree.

                                At best, what current LLMs are is evidence that linguistic processing follows statistically modelable rules.

                                raymaccarthy@mastodon.ieR weekend_editor@mathstodon.xyzW 2 Replies Last reply
                                0
                                • cstross@wandering.shopC cstross@wandering.shop

                                  But I'm REALLY HAPPY right now because this kinda-sorta validates the key premise of the SF novel I just handed in last month (which involves serial reincarnation via destructive brain-slicing-and-imaging then imprinting onto an immature cortex, and then explores its disastrous societal failure modes).

                                  ... And it also hints that artificial consciousness might, eventually, be possible, if only via the hard path of doing it the same way we do it, only in simulation in silico.

                                  /6 (ends)

                                  jsl@hachyderm.ioJ This user is from outside of this forum
                                  jsl@hachyderm.ioJ This user is from outside of this forum
                                  jsl@hachyderm.io
                                  wrote last edited by
                                  #19

                                  @cstross Does that make your work Science Fact-ion instead of Science Fiction?

                                  1 Reply Last reply
                                  0
                                  • cstross@wandering.shopC cstross@wandering.shop

                                    Sigh.

                                    So it turns out we've mapped the neural connectome of Drosophila *and simulated it in silico*.

                                    Link Preview Image
                                    FlyWire

                                    favicon

                                    (flywire.ai)

                                    Pop-sci explainer here:

                                    Link Preview Image
                                    Whole Brain Emulation Achieved: Scientists Run a Fruit Fly Brain in Simulation | RathBiotaClan

                                    Scientists ran a real fruit fly brain in simulation using the FlyWire connectome, achieving the first working whole brain emulation.

                                    favicon

                                    RathBiotaClan (www.rathbiotaclan.com)

                                    Key quote: "The step from a complete connectome to a working computational brain model is not trivial." And there's an even more important finding in this screenshot (alt text via OCR):

                                    "The wiring is the computation".

                                    /1

                                    dr2chase@ohai.socialD This user is from outside of this forum
                                    dr2chase@ohai.socialD This user is from outside of this forum
                                    dr2chase@ohai.social
                                    wrote last edited by
                                    #20

                                    @cstross "the wiring is the computer" is not too surprising. Years ago playing w/ algorithms for FPGA, needed to invent a bit-string perfect hash table. One way of doing a perfect hash function/table involves a matrix and offset, H = Mx + v, but our math needed to be boolean (AND, XOR), a "1" coefficient was a wire, and if we wanted a one-cycle hash index, then we needed no more 1's in a row than maximum inputs to an FPGA XOR. So, a sparse boolean matrix. The wiring was the computation..

                                    flippac@types.plF 1 Reply Last reply
                                    0
                                    • cstross@wandering.shopC cstross@wandering.shop

                                      But I'm REALLY HAPPY right now because this kinda-sorta validates the key premise of the SF novel I just handed in last month (which involves serial reincarnation via destructive brain-slicing-and-imaging then imprinting onto an immature cortex, and then explores its disastrous societal failure modes).

                                      ... And it also hints that artificial consciousness might, eventually, be possible, if only via the hard path of doing it the same way we do it, only in simulation in silico.

                                      /6 (ends)

                                      raymaccarthy@mastodon.ieR This user is from outside of this forum
                                      raymaccarthy@mastodon.ieR This user is from outside of this forum
                                      raymaccarthy@mastodon.ie
                                      wrote last edited by
                                      #21

                                      @cstross
                                      Also since cryogenic freezing a brain destroys the structure of an already dead brain (basically deteriotated), the folk paying for that are being scammed.

                                      I agree it's nice info for SF world building.

                                      Presumably they'd have to replace the blood of a living mouse with a special fluid to preserve the structure?

                                      cstross@wandering.shopC 1 Reply Last reply
                                      0
                                      • cstross@wandering.shopC cstross@wandering.shop

                                        @future_upbeat

                                        I absolutely agree.

                                        At best, what current LLMs are is evidence that linguistic processing follows statistically modelable rules.

                                        raymaccarthy@mastodon.ieR This user is from outside of this forum
                                        raymaccarthy@mastodon.ieR This user is from outside of this forum
                                        raymaccarthy@mastodon.ie
                                        wrote last edited by
                                        #22

                                        @cstross @future_upbeat
                                        Mostly but not entirely.

                                        1 Reply Last reply
                                        0
                                        • cstross@wandering.shopC cstross@wandering.shop

                                          But I'm REALLY HAPPY right now because this kinda-sorta validates the key premise of the SF novel I just handed in last month (which involves serial reincarnation via destructive brain-slicing-and-imaging then imprinting onto an immature cortex, and then explores its disastrous societal failure modes).

                                          ... And it also hints that artificial consciousness might, eventually, be possible, if only via the hard path of doing it the same way we do it, only in simulation in silico.

                                          /6 (ends)

                                          antiqueight@mastodon.ieA This user is from outside of this forum
                                          antiqueight@mastodon.ieA This user is from outside of this forum
                                          antiqueight@mastodon.ie
                                          wrote last edited by
                                          #23

                                          @cstross Wait- so... I should get my brain frozen until they perfect the slicing and uploading to silicon to live eternally

                                          cstross@wandering.shopC 1 Reply Last reply
                                          0
                                          Reply
                                          • Reply as topic
                                          Log in to reply
                                          • Oldest to Newest
                                          • Newest to Oldest
                                          • Most Votes


                                          • Login

                                          • Login or register to search.
                                          • First post
                                            Last post
                                          0
                                          • Categories
                                          • Recent
                                          • Tags
                                          • Popular
                                          • World
                                          • Users
                                          • Groups