<![CDATA[Happy birthday to 🇨🇦Canadian medical researcher &amp; #biochemist Maud Menten (1879-1960).]]>Happy birthday to 🇨🇦Canadian medical researcher & Maud Menten (1879-1960). Not only was she an author of Michaelis-Menten equation for kinetics, she invented the azo-dye coupling for alkaline phosphatase, 1st example of enzyme , still used in imaging of tissues today & she also performed the first separation of blood haemoglobin in 1944!⁠
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]]>https://board.circlewithadot.net/topic/fcf32d7a-e2ca-43cb-bb12-1d6b330bd851/happy-birthday-to-canadian-medical-researcher-amp-biochemist-maud-menten-1879-1960-.RSS for NodeMon, 06 Apr 2026 09:30:05 GMTFri, 20 Mar 2026 11:11:44 GMT60<![CDATA[Reply to Happy birthday to 🇨🇦Canadian medical researcher &amp; #biochemist Maud Menten (1879-1960). on Fri, 20 Mar 2026 11:14:40 GMT]]>She characterised bacterial toxins from B. paratyphosus, Streptococcus scarlatina & Salmonella ssp. then successfully used in an program against scarlet fever in Pittsburgh during the 30’s & 40’s. Promoted to assistant prof 1923 & assoc prof 1925, full prof in 1949 at 70, 1 year prior to retirement. Joined the BC Medical Research Institute & worked 3 more years. 🧵5/5

]]>https://board.circlewithadot.net/post/https://spore.social/users/minouette/statuses/116261210084628477https://board.circlewithadot.net/post/https://spore.social/users/minouette/statuses/116261210084628477Fri, 20 Mar 2026 11:14:40 GMT<![CDATA[Reply to Happy birthday to 🇨🇦Canadian medical researcher &amp; #biochemist Maud Menten (1879-1960). on Fri, 20 Mar 2026 11:14:33 GMT]]>clinical pathologist at Children’s Hospital in Pittsburgh. 3 positions: surgical pathologist, post-mortem pathologist, & haematologist & she authored > 100 papers. Discovered utility of immunization of animals against infectious diseases. In 1944 was 1st to use electric fields to separate different proteins in a mixture based on size - a method called electrophoresis - to separate blood (commonly misattributed to Pauling). 🧵4/5

]]>https://board.circlewithadot.net/post/https://spore.social/users/minouette/statuses/116261209590968677https://board.circlewithadot.net/post/https://spore.social/users/minouette/statuses/116261209590968677Fri, 20 Mar 2026 11:14:33 GMT<![CDATA[Reply to Happy birthday to 🇨🇦Canadian medical researcher &amp; #biochemist Maud Menten (1879-1960). on Fri, 20 Mar 2026 11:13:13 GMT]]>rate proportional to the amount of the enzyme-substrate complex, & developed their famous eq for rate as a function of substrate. Was critical to understanding how enzymes work &helped scientists develop means of blocking enzyme reactions. ⁠
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She studied cancer from 1913 to 1914 in lab of surgeon Crile at Western Reserve U in Cleveland. 2nd doctorate in biochem at U of Chicago in 1916. In 1923 she joined faculty of the U of Pittsburgh as a demonstrator in pathology & a 🧵3/

]]>https://board.circlewithadot.net/post/https://spore.social/users/minouette/statuses/116261204392774162https://board.circlewithadot.net/post/https://spore.social/users/minouette/statuses/116261204392774162Fri, 20 Mar 2026 11:13:13 GMT<![CDATA[Reply to Happy birthday to 🇨🇦Canadian medical researcher &amp; #biochemist Maud Menten (1879-1960). on Fri, 20 Mar 2026 11:12:37 GMT]]>Earned BSc in 1904, then M.B., bachelor’s of medicine in 1907 at U of Toronto. She published 1st paper on distribution of chloride ions in nerve cells in 1906. At Rockefeller Inst in NY, she co-authored book on radium bromide & cancer. She completed 1st of 2 fellowships at Western Reserve U (now Case Western), then earned medical research doctorate in 1911 at U of T. With Leonor Michaelis in Berlin looked at enzyme-catalyzed reactions, found they occurred at a 🧵2/

]]>https://board.circlewithadot.net/post/https://spore.social/users/minouette/statuses/116261201995153884https://board.circlewithadot.net/post/https://spore.social/users/minouette/statuses/116261201995153884Fri, 20 Mar 2026 11:12:37 GMT